ZEISS, a leading manufacturer of optical and optoelectronic technology, has announced the launch of their new microscopy technology, Lightfield 4D. This innovative technology, integrated into their new LSM 910 and LSM 990 confocal microscope systems, allows for high-speed fluorescence imaging of physiological and neuronal processes. With the ability to capture instant volumetric high-speed images, researchers can now observe the dynamic processes of life in complete samples with unprecedented temporal resolution.
According to Dr. Bernhard Zimmermann, Head of Life Sciences Microscopy at ZEISS, this new technology addresses the critical need for 4D imaging, combining volume and time to truly understand biological processes. Traditional optical sectioning techniques have long struggled with the limitations of sequential image acquisition, which introduces time delays and compromises the accuracy of data. ZEISS Lightfield 4D overcomes these challenges by imaging entire 3D data sets at a precise moment in time, eliminating time delays within a captured volume.
By utilizing a micro lens array, ZEISS Lightfield 4D can generate 37 individual images simultaneously, capturing comprehensive 3D information in real-time. This allows for the creation of Z-stacks through advanced deconvolution-based processing at an impressive rate of up to 80 volume Z-stacks per second. This technology is especially beneficial for studying rapid biological events such as physiological and neuronal processes.
In addition to its speed, ZEISS Lightfield 4D also reduces light exposure and phototoxic effects by capturing a complete Z-stack in one illumination event. This allows for long-term imaging of entire living organisms and enhances productivity of experiments across various applications. The unmatched speed of ZEISS Lightfield 4D also facilitates the capture of multi-color volumes of large samples, providing researchers with valuable insights into the dynamic nature of life.
To complement the launch of Lightfield 4D, ZEISS has also introduced enhanced versions of its LSM platforms: ZEISS LSM 910 and LSM 990. These upgraded systems feature new high-bandwidth electronics that support beampath technology for exceptional light preservation, visualization of high dynamic ranges, and a broad wavelength bandwidth. Additionally, image quality improvements with ZEISS Airyscan jDCV are now available for all Airyscan Multiplex modes. With the help of the Microscopy Copilot, a personal AI assistant, researchers can interactively explore new possibilities for their imaging experiments.
“We believe that Lightfield 4D will redefine the imaging landscape,” says Dr. Zimmermann. “This innovative system empowers researchers to capture biological processes in real-time, providing unprecedented insights into the dynamic nature of life.”
For more information on ZEISS Lightfield 4D, please visit: https://zeiss.ly/nw-lightfield-4d.
For press inquiries, please contact ZEISS Research Microscopy Solutions at press.microscopy@zeiss.com.
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